sharepoint 2010 - I want to know how to send an email to list of people -

sharepoint 2010 - I want to know how to send an email to list of people -

i need send alert several hundereds of recipienats. have names in excel sheet, of these fields might invalid entry. there anyway can create sharepoint accepts valid entries , auto-delete invalid ones, , proceed send emails. give thanks much

if emails sharepoint users, can cycle , check if users such emails exist. when have valid emails, append them 1 string added email's "to" section. hope helps

sharepoint-2010